UNM Rainforest Innovations

The U.S. Patent & Trademark Office (USPTO) recently issued eight U.S. patents to UNM Rainforest Innovations during the months of January, February, and March for technologies invented at the University of New Mexico. The patents, issued during UNM Rainforest Innovations’ 2023 fiscal third quarter, are for a variety of technologies created by researchers in the Departments of Neurology; Pharmacy; Pathology; Nanoscience & Microsystems; Computer Science; Chemical & Biological Engineering; Electrical & Computer Engineering; Language, Literacy, & Sociocultural Studies; and the Center for High Technology Materials.


Issued Patent for “Compositions and Methods for Treating Brain Injury
Patent No. 11,541,065, issued January 3, 2023
Inventors: Ranjana Poddar, Surojit Paul
(Ref. 2018-091)
Described here is a method for treating a hyperhomocysteinemic subject having cerebral ischemic stroke generally includes administering to the hyperhomocysteinemic subject, following cerebral stroke, a composition that includes an inhibitor or an antagonist of a GluN2A-containing N-methyl-D-aspartate receptor (NMDAR) in an amount effective to ameliorate at least one symptom or clinical sign of cerebral stroke.


Issued Patent for “Technologies for Energy-Modulated Radiation Therapy
Patent No. 11,559,703, issued January 24, 2023
Inventors: Richard Shaw, Shuang Luan
(Ref. 2017-076)
Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.


Issued Patent for “Dry Powder Nebulizer”
Patent No. 11,571,528, issued February 7, 2023
This technology is currently licensed.
Inventors: Nicola Jeanne Maynard, Hugh Smyth
(Ref. 2010-039)
This invention describes a dry powder delivery device that may be configured to provide micronized dry powder particles to airways of a user. The device may include a cylindrical container delimiting a chamber containing at least one magnetically-responsive object, a motor external to said chamber, a magnet external to the chamber and rotatably coupled with the motor, and an outflow member configured to direct airflow to a user. The magnetically-responsive object may be coated with micronized dry powder particles, and the motor may be operable to rotate the magnet about an axis. Rotation of the magnet creates a magnetic field that causes the magnetically-responsive object to move in response to the magnetic field and collide with a side wall of the container to deaggregate the dry powder particles and aerosolize the dry powder in the chamber.


Issued Patent for “Programmable Liquid, Gel, and Biohybrid Compartments and Methods of Use
Patent No. 11,583,819, issued February 21, 2023
Inventors: Gabriel Lopez, Joseph R. Simon, Nick J. Carroll, Ashutosh Chilkoti
(Ref. 2020-037)
Nano- to microscale liquid coacervate particles are provided. The liquid coacervate particles are produced by a process including stimulating a population of liquid droplets containing one or a mixture of components to induce a phase separation point of a first component, and maintaining stimulation at the phase separation point to form a coacervate domain of the first component within each of the droplets to form the liquid coacervate particles. The self-assembled nano, meso, micro and macro liquid coacervate particles and related coated substrates can have utility in drug delivery, bioanalytical systems, controlled cell culture, tissue engineering, biomanufacturing and drug discovery.


Issued Patent for “Electroplated Helical Slow-Wave Structures for High Frequency Signals
Patent No. 11,588,456, issued February 21, 2023
Inventors: Max Lagally, Matthew McLean Dwyer, Daniel Warren van der Weide, Abhishek Bhat, Francesca Cavallo, Divya Jyoti Prakash
(Ref. 2020-110)
Traveling-wave tube amplifiers and methods for making slow-wave structures for the amplifiers are provided. The SWSs include helical conductors that are self-assembled via the release of stressed electrically conductive strips from a sacrificial material. The helical conductors can be electroplated post-self-assembly to fortify the helix, reduce losses, and tailor the dimensions and operating parameters of the helix.


Issued Patent for “Rapid, culture free Detection of Drug Resistance Characteristics by Raman and Surface Enhanced Raman Spectroscopic Methods
Patent No. 11,592,399, issued February 28, 2023
Inventors: Aaron Kurt Neumann, Anatolly O’Pinchuk
(Ref. 2018-007)
The present invention provides highly sensitive assays for pathogen detection, identification and/or analysis including, but not limited to, sensing of metabolite patterns associated with high-risk drug resistance phenotypes.


Issued Patent for “System and Methods for Computing 2-D Convolutions and Cross-Correlations
Patent No. 11,593,907, issued February 28, 2023
Inventors: Marios Pattichis, Cesar Carranza, Daniel L. Obregon
(Ref. 2016-049)
Described here are fast and scalable architectures and methods adaptable to available resources, that (1) compute 2-D convolutions using 1-D convolutions, (2) provide fast transposition and accumulation of results for computing fast cross-correlations or 2-D convolutions, and (3) provide parallel computations using pipelined 1-D convolvers. Additionally, fast and scalable architectures and methods that compute 2-D linear convolutions using Discrete Periodic Radon Transforms (DPRTs) including the use of scalable DPRT, Fast DPRT, and fast 1-D convolutions.


Issued Patent for “Cross Slot Polarizer
Patent No. 11,594,796, issued February 28, 2023
Inventors: Firz Nazem Ayoub, Christos Christodoulou, Emil Ardelean, Steven Lane
(Ref. 2019-057)
This invention describes a polarizer including an antenna connected to a waveguide. The waveguide including a broad wall having a cross-slot in communication with at least one port.

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